Her defense of the president came in response to a question about Republican Senator Bob Corker's assertion that Trump's chief of staff and secretaries of state and defense "help separate our country from chaos".
She even joked about the comments, when CNN's Jim Acosta asked if she found it "satisfying" that the President had the power to make people "hold their breath, in this town, when he says something like that".
Asked again what he meant, Trump replied "you'll find out", and then left for a dinner with military brass and their spouses. A day later, Trump wrote in a pair of posts on Twitter, "I told Rex Tillerson, our wonderful secretary of state, that he is wasting his time trying to negotiate with Little Rocket Man".
Pressed on whether or not the public should take Trump's comments seriously, Sanders responded that the American people could take the president's commitment to national security seriously.
Trey Yingst of One America News asked Sanders if she thought the president wanted to see the Senate Intelligence Committee investigate media organizations. "We have a lot of bad actors in the world, North Korea, Iran, several examples there".
Reporters also peppered Sanders with questions about a nebulous comment Trump made about "the calm before the storm" during a Thursday photo-op with military families.
"We know that members of both parties and multiple organizations are planning to take a look at bump stocks and related devices", Sanders said during Thursday's regular press briefing.
Still, news outlets have run stories since then claiming that Trump and Tillerson have clashed over staff and policy on Iran and North Korea and that their relationship has been damaged beyond fix.