The duo have been mainstays in Jose Mourinho's side this season, but emerged as doubts for the crunch clash after missing weekend internationals for their respective countries.
Fellaini is set to miss Belgium's qualifier against Cyprus on Tuesday, and will miss United's match against Liverpool on Saturday.
Jones played 90 minutes in United's last game against Crystal Palace but was forced out of World Cup qualifiers against Slovenia and Lithuania with a knee problem.
Speaking to the media on Monday, Martinez said: "Marouane Fellaini, it has been confirmed that he has got ligament damage". I don't think the state of the pitch played any part.
However, the Manchester Evening News claim the player, having been assessed by United's medical team, has been given the all-clear to resume training and will very much be in contention for the trip to Anfield.
"Marouane is a very quick healer but obviously now we had the scan and it is damage in the ligament". 'But we knew that on Friday.
United are anxious Lukaku's ankle injury puts him in doubt for Saturday's clash with Liverpool in the Premier League.