The explosion, captured on videos making the round on social media, was reportedly caused by a tanker at a state-owned gas station around 7:30 pm local time.
Anaglatey said the Ghana fire service was now at a stage where it needs to upgrade its methods.
"Some people said there were flames in the skies, l looked and saw the flames and was convinced something awful had happened", said James Appiah, a resident of North Legon, about a kilometre (half a mile) from the explosion.
Deputy Ministers of Information, Mr Kojo Oppong Nkrumah and Perry Okudzeto, and some other high ranking government officials and the Inspector General of Police also took part in the visit.
Ghana's capital was the scene of a similar fire and explosion at a petrol station in June 2015 which killed more than 150. There were also 35 injured and five were in intensive care overnight.
George Agbey, who was close to the scene of the explosion, said: "There was some panic and we all just moved away from the scene".
On Sunday morning, burned steel frames show where the two gas stations were razed by the explosions.
Ambulances had been deployed, and those people who sustained various degrees of injury have been sent to hospitals, he said.
The Accra city authorities warned people to avoid the area.
A massive explosion has gone off at a petrol station in Ghana's capital, Accra, according to witnesses.