The 25-year-old sustained an injury in the previous game against Congo and has been advised by his club to rest after playing through pains recently.
The 2018 FIFA World Cup African Confederation qualifying group enters it's final phase as Uganda face The Black Stars of Ghana in Kampala on Saturday October 7th with a 1500 CEST kick-off.
Uganda Cranes host Madagascar in an worldwide friendly match today at the StarTimes stadium, Lugogo. "We are hoping to extend that form in Kampala", Appiah reportedly told Nation Sport. The team lies third in the group with five points and are four clear points of the pace of leaders Egypt with two matches to end the group.
Ghana coach Kwesi Appiah is facing some unforeseen challenges with his squad as injuries have left him short ahead of the crunch game against Uganda.
They now lie third in their group of four on five points - which is two behind second-placed Uganda and four behind group leaders Egypt.
Ghana, who are in Kenya for a training camp, are expected in Uganda today.
They include midfielder Kingsley Sarfo of Swedish side Malmo, defender Vincent Atings of Ghana premier league's Hearts of Oak and striker John Atwin of Egyptian side Misr Makkasa, all of whom trained with the team for the first time in Nairobi.
Is the Uganda v Ghana game online?
Christian Atsu has pulled out of the Ghana squad for upcoming World Cup qualifier against Uganda because of a calf problem.
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